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CyFlow™ TdT FITC

CyFlow™ TdT FITC
Alternative Name: Terminal transferase, DNTT, Terminal addition enzyme
Antigen: TdT
Clonality: monoclonal
Clone: 41A
Format/Fluorochrome: FITC
Isotype: IgG1, mouse
Target Species: Human
Product number: CE881363
$410.00 USD*

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  • Product number: CE881363
Description TDS & SDS
Description
Description The mouse monoclonal antibody 41A recognizes TdT (terminal deoxynucleotidyl... more
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CyFlow™ TdT FITC
Description The mouse monoclonal antibody 41A recognizes TdT (terminal deoxynucleotidyl transferase; an intracellular antigen), which is responsible for antigen receptor diversity in pre-B and pre-T lymphocytes.
Application The reagent may have application in various test methodologies, including flow cytometry. Vial has sufficient volume for 100 tests*, if used at 10 μL / test.
*ASR reagent – user has responsibility for determining reagent quantity per test for their own test application.
Purity ≤ 10% free (unconjugated) fluorochrome and/or monoclonal antibody, as measured by size-exclusion high performance liquid chromatography (SEC-HPLC).
Storage Buffer The reagent is provided in stabilising phosphate-buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) bovine serum albumin (BSA).
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Stability Do not use after expiration date stamped on vial label.
Antigen Distribution Terminal deoxynucleotidyl transferase (TdT) is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. It is expressed in restricted populations of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
Warnings All biological specimens and materials coming in contact with them are considered biohazards. Handle as if capable of transmitting infection and dispose of with proper precautions in accordance with federal, state and local regulations. Never pipette by mouth. Wear suitable protective clothing, eyewear and gloves.
Non-Hazardous Statement: This is not considered hazardous by the criteria in 29 CFR 1910.1200 or the
General Classification guideline for preparations of the EU. November 2024
Safety Data Sheet Statement: Important information regarding the safe handling, transport, and disposal of this product is contained in the Safety Data Sheet.
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