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CyFlow™ CD28 APC
| Alternative Name: | Tp44 |
| Antigen: | CD28 |
| Clonality: | monoclonal |
| Clone: | CD28.2 |
| Format/Fluorochrome: | APC |
| Isotype: | IgG1, mouse |
| Target Species: | Human |
| Product number: | CA369784 |
- Product number: CA369784
| Alternative Name: | Tp44 |
| Antigen: | CD28 |
| Clonality: | monoclonal |
| Clone: | CD28.2 |
| Format/Fluorochrome: | APC |
| Isotype: | IgG1, mouse |
| Target Species: | Human |
| Product number: | CA369784 |
| Description | The mouse monoclonal antibody CD28.2 recognizes human CD28 antigen. |
| Application | The reagent may have application in various test methodologies, including flow cytometry. Vial has sufficient volume for 100 tests*, if used at 10 μL / test. *ASR reagent – user has responsibility for determining reagent quantity per test for their own test application. |
| Purity | ≤ 20% free (unconjugated) fluorochrome and/or monoclonal antibody, as measured by size-exclusion high performance liquid chromatography (SEC-HPLC). |
| Storage Buffer | The reagent is provided in stabilising phosphate-buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) bovine serum albumin (BSA). |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
| Antigen Distribution | CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. |
| Warnings | All biological specimens and materials coming in contact with them are considered biohazards. Handle as if capable of transmitting infection and dispose of with proper precautions in accordance with federal, state and local regulations. Never pipette by mouth. Wear suitable protective clothing, eyewear and gloves. Non-Hazardous Statement: This is not considered hazardous by the criteria in 29 CFR 1910.1200 or the General Classification guideline for preparations of the EU. November 2024 Safety Data Sheet Statement: Important information regarding the safe handling, transport, and disposal of this product is contained in the Safety Data Sheet. |