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CyFlow™ CD14 PE-Cy7
| Alternative Name: | LPS-R |
| Antigen: | CD14 |
| Clonality: | monoclonal |
| Clone: | MEM-15 |
| Format/Fluorochrome: | PE-Cy7 |
| Isotype: | IgG1, mouse |
| Target Species: | Human |
| Product number: | BW161805 |
- Product number: BW161805
Description The mouse monoclonal antibody MEM-15 recognizes human CD14 antigen. HLDA... more
CyFlow™ CD14 PE-Cy7
| Description | The mouse monoclonal antibody MEM-15 recognizes human CD14 antigen. HLDA III-WS Code M 252 HLDA IV-WS Code N 90 HLDA IV-WS Code T 53 HLDA IV-WS Code M313 HLDA V-WS Code MA86 HLDA VI-WS Code MA94 |
| Application | The reagent may have application in various test methodologies, including flow cytometry. Vial has sufficient volume for 100 tests*, if used at 10 μL / test. *ASR reagent – user has responsibility for determining reagent quantity per test for their own test application. |
| Purity | ≤ 20% free (unconjugated) fluorochrome and/or monoclonal antibody, as measured by size-exclusion high performance liquid chromatography (SEC-HPLC). |
| Storage Buffer | The reagent is provided in stabilising phosphate-buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) bovine serum albumin (BSA). |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
| Antigen Distribution | CD14 (LPS-R) is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. |
| Warnings | All biological specimens and materials coming in contact with them are considered biohazards. Handle as if capable of transmitting infection and dispose of with proper precautions in accordance with federal, state and local regulations. Never pipette by mouth. Wear suitable protective clothing, eyewear and gloves. Non-Hazardous Statement: This is not considered hazardous by the criteria in 29 CFR 1910.1200 or the General Classification guideline for preparations of the EU. November 2024 Safety Data Sheet Statement: Important information regarding the safe handling, transport, and disposal of this product is contained in the Safety Data Sheet. |