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CyFlow™ CD11b APC-Cy7

CyFlow™ CD11b APC-Cy7
Alternative Name: Mac-1
Antibody: Yes
Antigen: CD11b
Clonality: monoclonal
Clone: ICRF44
Emission Maximum: 780 nm
Excitation Maximum: 650 nm, 750 nm
Field of Interest: Immunophenotyping
Format/Fluorochrome: APC-Cy7
Isotype: IgG1, mouse
Laser: Red
Regulatory Status: ASR
Source Species: Mouse
Target Species: Human
Product number: CB102695
$540.00 USD*

Price excludes any applicable taxes plus shipping costs

  • Product number: CB102695
Description TDS & SDS
Description
Description The mouse monoclonal antibody ICRF44 recognizes human CD11b antigen. HLDA... more
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CyFlow™ CD11b APC-Cy7
Description The mouse monoclonal antibody ICRF44 recognizes human CD11b antigen.
HLDA IV-WS Code M047
Application The reagent may have application in various test methodologies, including flow cytometry. Vial has sufficient volume for 100 tests*, if used at 10 μL / test.
*ASR reagent – user has responsibility for determining reagent quantity per test for their own test application.
Purity ≤ 20% free (unconjugated) fluorochrome and/or monoclonal antibody, as measured by size-exclusion high performance liquid chromatography (SEC-HPLC).
Storage Buffer The reagent is provided in stabilising phosphate-buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) bovine serum albumin (BSA).
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Stability Do not use after expiration date stamped on vial label.
Antigen Distribution CD11b (integrin αM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with CD18 (integrin β2 subunit); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.
Warnings All biological specimens and materials coming in contact with them are considered biohazards. Handle as if capable of transmitting infection and dispose of with proper precautions in accordance with federal, state and local regulations. Never pipette by mouth. Wear suitable protective clothing, eyewear and gloves.
Non-Hazardous Statement: This is not considered hazardous by the criteria in 29 CFR 1910.1200 or the
General Classification guideline for preparations of the EU. November 2024
Safety Data Sheet Statement: Important information regarding the safe handling, transport, and disposal of this product is contained in the Safety Data Sheet.
TDS & SDS
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Technical Data Sheet