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CyFlow™ IgD PE
Antigen: | IgD |
Clonality: | monoclonal |
Clone: | IA6-2 |
Format/Fluorochrome: | PE |
Isotype: | mouse |
Target Species: | Human |
Product number: | BM781357 |
- Product number: BM781357
Antigen: | IgD |
Clonality: | monoclonal |
Clone: | IA6-2 |
Format/Fluorochrome: | PE |
Isotype: | mouse |
Target Species: | Human |
Product number: | BM781357 |
Description | The mouse monoclonal antibody IA6-2 recognizes human IgD antigen. |
Application | The reagent may have application in various test methodologies, including flow cytometry. Vial has sufficient volume for 100 tests*, if used at 10 μL / test. *ASR reagent – user has responsibility for determining reagent quantity per test for their own test application. |
Purity | ≤ 20% free (unconjugated) fluorochrome and/or monoclonal antibody, as measured by size-exclusion high performance liquid chromatography (SEC-HPLC). |
Storage Buffer | The reagent is provided in stabilising phosphate-buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage and Stability | Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. Stability: Do not use after expiration date stamped on vial label. |
Antigen Distribution | Immunoglobulin D (IgD) is expressed on the surface of naive mature B cells. Triggered by antigen binding, it signals through the CD79 complex to activate the B cells. Expression of IgD is lost after the isotype switch. Soluble IgD is present in very small amounts in the serum. IgD can bind to basophils and mast cells to activate them in an IgE-independent way to participate in respiratory immune defense. |
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