CyFlow™ CD71 Alexa Fluor™ 700

Alternative Name:	T9 , TFR, TRFR
Antibody:	Yes
Antigen:	CD71
Clonality:	monoclonal
Clone:	MEM-75
Emission Maximum:	723 nm
Excitation Maximum:	702 nm
Field of Interest:	Endocytosis, Immunophenotyping
Format/Fluorochrome:	Alexa Fluor™ 700
Isotype:	IgG1
Laser:	Red
Regulatory Status:	ASR
Source Species:	Mouse
Target Species:	Human
Product number:	CY779764

Analytical and performance characteristics are not established

$495.00 USD*

Price excludes any applicable taxes plus shipping costs

HLDA Workshop HLDA IV—WS Code A 45 HLDA V—WS Code T T-165 Concentration Unit µg/mL... more

CyFlow™ CD71 Alexa Fluor™ 700

HLDA Workshop	HLDA IV—WS Code A 45 HLDA V—WS Code T T-165
Concentration Unit	µg/mL
Concentration	100
Volume	1.0 mL
Immunogen	NALM-6 human pre-B cell line
Antigen Distribution	CD71 (T9, TFR, TRFR) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.
Usage	The reagent may have application in various test methodologies, including Flow Cytometry. Vial has sufficient volume for 100 tests, if used at 10 μL·/·test. User has responsibility for determining reagent quantity per test for any ASR reagent.
Storage Buffer	The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
Storage	Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Stability	Do not use after expiration date stamped on vial label.

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