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CyFlow™ CD11b PE-Cy7

CyFlow™ CD11b PE-Cy7
Alternative Name: Mac-1
Antibody: Yes
Antigen: CD11b
Clonality: monoclonal
Clone: ICRF44
Emission Maximum: 785 nm
Excitation Maximum: 496 nm, 565 nm
Field of Interest: Immunophenotyping
Format/Fluorochrome: PE-Cy7
Isotype: IgG1
Laser: Blue , Green, Yellow
Regulatory Status: ASR
Source Species: Mouse
Target Species: Human
Product number: CB652124

Analytical and performance characteristics are not established

$495.00 USD*

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HLDA Workshop HLDA IV—WS Code M047 Concentration Unit µg/mL Concentration 60... more
CyFlow™ CD11b PE-Cy7

HLDA WorkshopHLDA IV—WS Code M047
Concentration Unitµg/mL
Concentration60
Volume1.0 mL
ImmunogenRheumatoid synovial cells and human monocytes
Antigen DistributionCD11b (integrin αM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with CD18 (integrin β2 subunit); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.
UsageThe reagent may have application in various test methodologies, including Flow Cytometry. Vial has sufficient volume for 100 tests, if used at 10 μL·/·test. User has responsibility for determining reagent quantity per test for any ASR reagent.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

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