CyFlow™ CD19 PE-Cy7

Alternative Name:	B4
Antibody:	Yes
Antigen:	CD19
Clonality:	monoclonal
Clone:	LT19
Emission Maximum:	785 nm
Excitation Maximum:	496 nm, 565 nm
Field of Interest:	Immunophenotyping
Format/Fluorochrome:	PE-Cy7
Isotype:	IgG1
Laser:	Blue , Green, Yellow
Regulatory Status:	ASR
Source Species:	Mouse
Target Species:	Human
Product number:	BE394220

Analytical and performance characteristics are not established

$495.00 USD*

Price excludes any applicable taxes plus shipping costs

HLDA Workshop HCDM/HLDA 10 Concentration Unit µg/mL Concentration 30 Volume 1.0... more

Close menu

CyFlow™ CD19 PE-Cy7

HLDA Workshop	HCDM/HLDA 10
Concentration Unit	µg/mL
Concentration	30
Volume	1.0 mL
Immunogen	Daudi human Burkitt lymphoma cell line
Antigen Distribution	CD19 (B4) is a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells; it is lost on plasma cells.
Usage	The reagent may have application in various test methodologies, including Flow Cytometry. Vial has sufficient volume for 100 tests, if used at 10 μL·/·test. User has responsibility for determining reagent quantity per test for any ASR reagent.
Storage Buffer	The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
Storage	Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Stability	Do not use after expiration date stamped on vial label.

Specific References

| Fujimoto M, Poe JC, Jansen PJ, Sato S, Tedder TF: CD19 amplifies B lymphocyte signal transduction by regulating Src‑family protein tyrosine kinase activation. J·Immunol. 1999·Jun·15; 162(12):7088‑94. <·PMID:·10358152·> | Inabe K, Kurosaki T: Tyrosine phosphorylation of B‑cell adaptor for phosphoinositide 3‑kinase is required for Akt activation in response to CD19 engagement. Blood. 2002·Jan·15; 99(2):584‑9. <·PMID:·11781242·> | Elias F, Flo J, Lopez RA, Zorzopulos J, Montaner A, Rodriguez JM: Strong cytosine‑guanosine‑independent immunostimulation in humans and other primates by synthetic oligodeoxynucleotides with PyNTTTTGT motifs. J·Immunol. 2003·Oct·1; 171(7):3697‑704. <·PMID:·14500668·> | Lin CW, Liu TY, Chen SU, Wang KT, Medeiros LJ, Hsu SM: CD94 1A transcripts characterize lymphoblastic lymphoma/leukemia of immature natural killer cell origin with distinct clinical features. Blood. 2005·Nov·15; 106(10):3567‑74. <·PMID:·16046525·> | van Zelm MC, Reisli I, van der Burg M, Castaño D, van Noesel CJ, van Tol MJ, Woellner C, Grimbacher B, Patiño PJ, van Dongen JJ, Franco JL: An antibody‑deficiency syndrome due to mutations in the CD19 gene. N·Engl·J·Med. 2006·May·4; 354(18):1901‑12. <·PMID:·16672701·> | Shi X, Xie C, Chang S, Zhou XJ, Tedder T, Mohan C: CD19 hyperexpression augments Sle1‑induced humoral autoimmunity but not clinical nephritis. Arthritis·Rheum. 2007·Sep; 56(9):3057‑69. <·PMID:·17763445·> | Stehlíková O, Chovancová J, Tichý B, Krejčí M, Brychtová Y, Panovská A, Francová Skuhrová H, Burčková K, Borský M, Loja T, Mayer J, Pospíšilová S, Doubek M: Detecting minimal residual disease in patients with chronic lymphocytic leukemia using 8‑color flow cytometry protocol in routine hematological practice. Int·J·Lab·Hematol. 2014·Apr; 36(2):165‑71. <·PMID:·24028768·>

Close menu

Technical Support - (888) 879-7639, option 1
Customer Service - (888) 879-7639, option 5
Sales - cytometry@sysmex.com

Technical Data Sheet

Safety Data Sheet

CyFlow Monoclonal Antibodies SDS