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CyFlow™ HLA-E Purified

CyFlow™ HLA-E Purified
Antibody: Yes
Antigen: HLA-E
Application: Flow cytometry, Immunoprecipitation
Clonality: monoclonal
Clone: MEM-E/08
Field of Interest: MHC
Format/Fluorochrome: Purified
Isotype: IgG1
Regulatory Status: RUO
Source Species: Mouse
Target Species: Human
Product number: CT617431

For Research Use Only

$120.00 USD*

Price excludes any applicable taxes plus shipping costs

Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
CyFlow™ HLA-E Purified
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenBacterially expressed recombinant HLA-E refolded with β2-microglobulin and peptide
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

| Sibilio L, et al.: Abstract 45 from the 3rd International Conference on HLA‑G; Paris, July 2003. Tissue Antigens. 2003; 62:339. < No PMID > | Palmisano GL, Contardi E, Morabito A, Gargaglione V, Ferrara GB, Pistillo MP: HLA‑E surface expression is independent of the availability of HLA class I signal sequence‑derived peptides in human tumor cell lines. Hum Immunol. 2005 Jan; 66(1):42705. < PMID: 15620456 > | Gonen-Gross T, Achdout H, Arnon TI, Gazit R, Stern N, Horejsí V, Goldman-Wohl D, Yagel S, Mandelboim O: The CD85J/leukocyte inhibitory receptor‑1 distinguishes between conformed and beta 2‑microglobulin‑free HLA‑G molecules. J Immunol. 2005 Oct 15; 175(8):4866‑74. < PMID: 16210588 > | Lo Monaco E, Tremante E, Cerboni C, Melucci E, Sibilio L, Zingoni A, Nicotra MR, Natali PG, Giacomini P: Human leukocyte antigen E contributes to protect tumor cells from lysis by natural killer cells. Neoplasia. 2011 Sep; 13(9):822‑30. < PMID: 21969815 > | Nachmani D, Zimmermann A, Oiknine Djian E, Weisblum Y, Livneh Y, Khanh Le VT, Galun E, Horejsi V, Isakov O, Shomron N, Wolf DG, Hengel H, Mandelboim O: MicroRNA editing facilitates immune elimination of HCMV infected cells. PLoS Pathog. 2014 Feb 27; 10(2):e1003963. < PMID: 24586166 >