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CyFlow™ CD261 Purified

CyFlow™ CD261 Purified
Alternative Name: APO2, DR4, TNFRSF10a, TRAILR1
Antibody: Yes
Antigen: CD261
Application: Flow cytometry, Functional assays, Immunocytochemistry, Immunoprecipitation
Clonality: monoclonal
Clone: DR-4-02
Field of Interest: Apoptosis, Immunophenotyping
Format/Fluorochrome: Purified
Isotype: IgG1
Regulatory Status: RUO
Source Species: Mouse
Target Species: Human
Product number: AJ695096

For Research Use Only

$120.00 USD*

Price excludes any applicable taxes plus shipping costs

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Description
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
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CyFlow™ CD261 Purified
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenFusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1
Background InformationCD261 (TRAIL-R1; TRAIL receptor 1 or DR4) is a type I transmembrane protein. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF κB activation in many cells and tissues.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

| Corallini F, Milani D, Nicolin V, Secchiero P: TRAIL, caspases and maturation of normal and leukemic myeloid precursors. . Leuk Lymphoma. 2006 Aug; 47(8):1459‑6. < PMID: 16966254 > | Simova S, Klima M, Cermak L, Sourkova V, Andera L: Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL‑R1/DR4 to the plasma membrane. Apoptosis. 2008 Mar; 13(3):423‑36. < PMID: 18165900 >

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