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CyFlow™ CD261 Low Endotoxin

CyFlow™ CD261 Low Endotoxin
Alternative Name: APO2, DR4, TNFRSF10a, TRAILR1
Antibody: Yes
Antigen: CD261
Application: Flow cytometry, Functional assays, Immunocytochemistry, Immunoprecipitation
Clonality: monoclonal
Clone: DR-4-02
Field of Interest: Apoptosis, Immunophenotyping
Format/Fluorochrome: Low Endotoxin
Isotype: IgG1
Regulatory Status: RUO
Source Species: Mouse
Target Species: Human
Product number: AV940775

For Research Use Only

$130.00 USD*

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Description
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
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CyFlow™ CD261 Low Endotoxin
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenFusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1
Background InformationCD261 (TRAIL-R1; TRAIL receptor 1 or DR4) is a type I transmembrane protein. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF κB activation in many cells and tissues.
Storage BufferThe reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

| Corallini F, Milani D, Nicolin V, Secchiero P: TRAIL, caspases and maturation of normal and leukemic myeloid precursors. . Leuk Lymphoma. 2006 Aug; 47(8):1459‑6. < PMID: 16966254 > | Simova S, Klima M, Cermak L, Sourkova V, Andera L: Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL‑R1/DR4 to the plasma membrane. Apoptosis. 2008 Mar; 13(3):423‑36. < PMID: 18165900 >

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