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CyFlow™ CD261 APC

CyFlow™ CD261 APC
Alternative Name: APO2, DR4, TNFRSF10a, TRAILR1
Antibody: Yes
Antigen: CD261
Application: Flow cytometry
Clonality: monoclonal
Clone: DR-4-02
Emission Maximum: 660 nm
Excitation Maximum: 650 nm
Field of Interest: Apoptosis, Immunophenotyping
Format/Fluorochrome: APC
Isotype: IgG1
Laser: Red
Regulatory Status: RUO
Source Species: Mouse
Target Species: Human
Product number: AD984868

For Research Use Only

$255.00 USD*

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Description
Concentration Unit mg/mL Concentration 0,1 Quantity 0.1 mg Volume 1.0 mL... more
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CyFlow™ CD261 APC
Concentration Unitmg/mL
Concentration0,1
Quantity0.1 mg
Volume1.0 mL
ImmunogenFusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1
Background InformationCD261 (TRAIL-R1; TRAIL receptor 1 or DR4) is a type I transmembrane protein. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF κB activation in many cells and tissues.
UsageThe reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

| Corallini F, Milani D, Nicolin V, Secchiero P: TRAIL, caspases and maturation of normal and leukemic myeloid precursors. . Leuk Lymphoma. 2006 Aug; 47(8):1459‑6. < PMID: 16966254 > | Simova S, Klima M, Cermak L, Sourkova V, Andera L: Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL‑R1/DR4 to the plasma membrane. Apoptosis. 2008 Mar; 13(3):423‑36. < PMID: 18165900 >

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