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CyFlow™ CD197 Purified

CyFlow™ CD197 Purified
Alternative Name: BLR2, CCR7 , CMKBR7, EB11
Antibody: Yes
Antigen: CD197
Application: Flow cytometry, Immunoprecipitation
Clonality: monoclonal
Clone: 4B12
Field of Interest: Immunophenotyping, MHC
Format/Fluorochrome: Purified
Isotype: IgG2a
Regulatory Status: RUO
Source Species: Rat
Target Species: Mouse
Product number: CL718383

For Research Use Only

$120.00 USD*

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Description
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
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CyFlow™ CD197 Purified
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenMouse CD197-transfected RBL-2H3 cells
Background InformationCD197 (CCR7; chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

| Huggins A, Paschalidis N, Flower RJ, Perretti M, D'Acquisto F: Annexin‑1‑deficient dendritic cells acquire a mature phenotype during differentiation. FASEB J. 2009 Apr; 23(4):985‑96. < PMID: 19029200 > | Singh V, Gowthaman U, Jain S, Parihar P, Banskar S, Gupta P, Gupta UD, Agrewala JN: Coadministration of interleukins 7 and 15 with bacille Calmette‑Guérin mounts enduring T cell memory response against Mycobacterium tuberculosis. J Infect Dis. 2010 Aug 15; 202(3):480‑9. < PMID: 20569158 > | Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG, Xu L, Zenewicz LA, Haberman AM, Elinav E, Kleinstein SH, Sutterwala FS, Flavell RA: NLRP10 is a NOD‑like receptor essential to initiate adaptive immunity by dendritic cells. Nature. 2012 Apr 25; 484(7395):510‑3. < PMID: 22538615 > | Adachi K, Osada Y, Nakamura R, Tamada K, Hamano S: Unique T Cells with Unconventional Cytokine Profiles Induced in the Livers of Mice during Schistosoma mansoni Infection. PLoS One. 2013 Dec 16; 8(12):e82698. < PMID: 24358216 >

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