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CyFlow™ CD41 PE

CyFlow™ CD41 PE
Alternative Name: gpIIb
Antibody: Yes
Antigen: CD41
Application: Flow cytometry
Clonality: monoclonal
Clone: MWReg30
Emission Maximum: 576 nm
Excitation Maximum: 496 nm, 565 nm
Field of Interest: Immunophenotyping, MHC
Format/Fluorochrome: PE
Isotype: IgG1
Laser: Blue , Green, Yellow
Regulatory Status: RUO
Source Species: Rat
Target Species: Mouse
Product number: BQ684614

For Research Use Only

$255.00 USD*

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Description Documentation TDS & SDS
Description
Concentration Unit mg/mL Concentration 0,5 Quantity 0.1 mg Volume 0.2 mL... more
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CyFlow™ CD41 PE

Concentration Unitmg/mL
Concentration0,5
Quantity0.1 mg
Volume0.2 mL
ImmunogenMouse platelets
Background InformationCD41 (GPIIb; platelet glycoprotein IIb) is composed of two subunits (120 kDa GPIIb α and 23 kDa GPIIb β) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
UsageThe reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

Specific References

| Sullivan BP, Wang R, Tawfik O, Luyendyk JP: Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies. Toxicol Sci. 2010 May; 115(1):286‑94. < PMID: 20133375 > | Boisset JC, Clapes T, Van Der Linden R, Dzierzak E, Robin C: Integrin αIIb (CD4{01} plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta. Biol Open. 2013 Apr 11; 2(5):525‑32. < PMID: 23789102 > | Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S, Perretti M: A vasculo‑protective circuit centered on lipoxin A4 and aspirin‑triggered 15‑epi‑lipoxin A4 operative in murine microcirculation. Blood. 2013 Jul 25; 122(4):608‑17. < PMID: 23733341 > | Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX: Stress‑induced hematopoietic failure in the absence of immediate early response gene X‑1. Haematologica. 2013 Sep 20; < PMID: 23812939 >

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