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CyFlow™ CD21 Alexa Fluor™ 647

CyFlow™ CD21 Alexa Fluor™ 647
Alternative Name: C3dR , CR2, EBV-R
Antibody: Yes
Antigen: CD21
Application: Flow cytometry
Clonality: monoclonal
Clone: LT21
Emission Maximum: 665 nm
Excitation Maximum: 650 nm
Field of Interest: Immunophenotyping
Format/Fluorochrome: Alexa Fluor™ 647
Isotype: IgG1
Laser: Red
Regulatory Status: RUO
Source Species: Mouse
Target Species: Cow, Dog, Human, Pig
Product number: CT467212

For Research Use Only

$285.00 USD*

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HLDA Workshop HLDA VI—WS Code B CD21.1 Quantity 100 tests Volume 0.4 mL Immunogen... more
CyFlow™ CD21 Alexa Fluor™ 647
HLDA WorkshopHLDA VI—WS Code B CD21.1
Quantity100 tests
Volume0.4 mL
ImmunogenIM9 human B-lymphoblastoid cell line
Background InformationCD21 (CR2; complement receptor 2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

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